Publications

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2021

Schorn, Michelle A; Verhoeven, Stefan; Ridder, Lars; Huber, Florian; Acharya, Deepa D; Aksenov, Alexander A; Aleti, Gajender; Moghaddam, Jamshid Amiri; Aron, Allegra T; Aziz, Saefuddin; Bauermeister, Anelize; Bauman, Katherine D; Baunach, Martin; Beemelmanns, Christine; Beman, Michael J; Berlanga-Clavero, María Victoria; Blacutt, Alex A; Bode, Helge B; Boullie, Anne; Brejnrod, Asker; Bugni, Tim S; Calteau, Alexandra; Cao, Liu; Carrión, Víctor J; Castelo-Branco, Raquel; Chanana, Shaurya; Chase, Alexander B; Chevrette, Marc G; Costa-Lotufo, Leticia V; Crawford, Jason M; Currie, Cameron R; Cuypers, Bart; Dang, Tam; de Rond, Tristan; Demko, Alyssa M; Dittmann, Elke; Du, Chao; Drozd, Christopher; Dujardin, Jean-Claude; Dutton, Rachel J; Edlund, Anna; Fewer, David P; Garg, Neha; Gauglitz, Julia M; Gentry, Emily C; Gerwick, Lena; Glukhov, Evgenia; Gross, Harald; Gugger, Muriel; Matus, Dulce G Guillén; Helfrich, Eric J N; Hempel, Benjamin-Florian; Hur, Jae-Seoun; Iorio, Marianna; Jensen, Paul R; Kang, Kyo Bin; Kaysser, Leonard; Kelleher, Neil L; Kim, Chung Sub; Kim, Ki Hyun; Koester, Irina; König, Gabriele M; Leao, Tiago; Lee, Seoung Rak; Lee, Yi-Yuan; Li, Xuanji; Little, Jessica C; Maloney, Katherine N; Männle, Daniel; H., Christian Martin; McAvoy, Andrew C; Metcalf, Willam W; Mohimani, Hosein; Molina-Santiago, Carlos; Moore, Bradley S; Mullowney, Michael W; Muskat, Mitchell; Nothias, Louis-Félix; O'Neill, Ellis C; Parkinson, Elizabeth I; Petras, Daniel; Piel, Jörn; Pierce, Emily C; Pires, Karine; Reher, Raphael; Romero, Diego; Roper, Caroline M; Rust, Michael; Saad, Hamada; Saenz, Carmen; Sanchez, Laura M; Sørensen, Søren Johannes; Sosio, Margherita; Süssmuth, Roderich D; Sweeney, Douglas; Tahlan, Kapil; Thomson, Regan J; Tobias, Nicholas J; Trindade-Silva, Amaro E; van Wezel, Gilles P; Wang, Mingxun; Weldon, Kelly C; Zhang, Fan; Ziemert, Nadine; Duncan, Katherine R; Crüsemann, Max; Rogers, Simon; Dorrestein, Pieter C; Medema, Marnix H; van der Hooft, Justin J J

A community resource for paired genomic and metabolomic data mining Journal Article

In: Nature Chemical Biology, 2021, ISSN: 1552-4469.

Abstract | Links | BibTeX | Altmetric | Tags: genomics, metabolomics, multi-omics

Hefnawy, Aya; Negreira, Gabriel; Jara, Marlene; Cotton, James A; Maes, Ilse; Haenens, Erika Dtextquoteright; Imamura, Hideo; Cuypers, Bart; Monsieurs, Pieter; Mouchtoglou, Christina; Winter, Hans De; Berriman, Matt; Sanders, Mandy; Martin, Julio; de Muylder, Geraldine; Dujardin, Jean-Claude; Sterckx, Yann G -J; Domagalska, Malgorzata Anna

Genomic and phenotypic characterization of experimentally selected resistant Leishmania donovani reveals a role for dynamin-1 like protein in the mechanism of resistance to a novel anti-leishmanial compound Journal Article

In: bioRxiv, 2021.

Abstract | Links | BibTeX | Altmetric | Tags: drug-resistance, genomics, leishmania

Boullosa, Laurie Freire; Loenhout, Jinthe Van; Flieswasser, Tal; Waele, Jorrit De; Hermans, Christophe; Lambrechts, Hilde; Cuypers, Bart; Laukens, Kris; Bartholomeus, Esther; Siozopoulou, Vasiliki; Vos, Winnok H De; Peeters, Marc; Smits, Evelien L J; Deben, Christophe

Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer Journal Article

In: Redox Biology, pp. 101949, 2021, ISSN: 2213-2317.

Abstract | Links | BibTeX | Altmetric | Tags: cancer, genomics, RNA-seq, transcriptomics

2020

Cuypers, Bart; Dumetz, Franck; Meysman, Pieter; Laukens, Kris; Muylder, Géraldine De; Dujardin, Jean-Claude; Domagalska, Malgorzata Anna

The Absence of C-5 DNA Methylation in Leishmania donovani Allows DNA Enrichment from Complex Samples Journal Article

In: Microorganisms, 8 (8), 2020, ISSN: 2076-2607.

Abstract | Links | BibTeX | Altmetric | Tags: bisulfite-sequencing, genomics, leishmania

Uzureau, Sophie; Lecordier, Laurence; Uzureau, Pierrick; Hennig, Dorle; Graversen, Jonas H; Homblé, Fabrice; Mfutu, Pepe Ekulu; Arcolino], Fanny [Oliveira; Ramos, Ana Raquel; Rovere], Rita [La M; Luyten, Tomas; Vermeersch, Marjorie; Tebabi, Patricia; Dieu, Marc; Cuypers, Bart; Deborggraeve, Stijn; Rabant, Marion; Legendre, Christophe; Moestrup, Søren K; Levtchenko, Elena; Bultynck, Geert; Erneux, Christophe; Pérez-Morga, David; Pays, Etienne

APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin Journal Article

In: Cell Reports, 30 (11), pp. 3821 - 3836.e13, 2020, ISSN: 2211-1247.

Abstract | Links | BibTeX | Altmetric | Tags: genomics

2018

Cuypers, Bart; Berg, Maya; Imamura, Hideo; Dumetz, Franck; Muylder], Géraldine [De; Domagalska, Malgorzata A; Rijal, Suman; Bhattarai, Narayan Raj; Maes, Ilse; Sanders, Mandy; Cotton, James A; Meysman, Pieter; Laukens, Kris; Dujardin, Jean-Claude

Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent Journal Article

In: Infection, Genetics and Evolution, 62 , pp. 170 - 178, 2018, ISSN: 1567-1348.

Abstract | Links | BibTeX | Altmetric | Tags: genomics, LC-MS, metabolomics, multi-omics

Cuypers, Bart

A systems biology approach for a comprehensive understanding of molecular adaptation in** Leishmania donovani PhD Thesis

University of Antwerp, 2018.

BibTeX | Tags: genomics, LC-MS, leishmania, multi-omics, proteomics, RNA-seq, transcriptomics

2017

Cuypers, Bart; den Broeck, Frederik Van; Reet, Nick Van; Meehan, Conor J; Cauchard, Julien; Wilkes, Jonathan M; Claes, Filip; Goddeeris, Bruno; Birhanu, Hadush; Dujardin, Jean-Claude; Laukens, Kris; Büscher, Philippe; Deborggraeve, Stijn

Genome-Wide SNP Analysis Reveals Distinct Origins of Trypanosoma evansi and Trypanosoma equiperdum Journal Article

In: Genome Biology and Evolution, 9 (8), pp. 1990-1997, 2017, ISSN: 1759-6653.

Abstract | Links | BibTeX | Altmetric | Tags: evolution, genomics

Dumetz, F; Imamura, H; Sanders, M; Seblova, V; Myskova, J; Pescher, P; Vanaerschot, M; Meehan, C J; Cuypers, B; Muylder, G De; Späth, G F; Bussotti, G; Vermeesch, J R; Berriman, M; Cotton, J A; Volf, P; Dujardin, J C; Domagalska, M A

Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression Journal Article

In: mBio, 8 (3), 2017.

Abstract | Links | BibTeX | Altmetric | Tags: genomics, leishmania, multi-omics, RNA-seq, transcriptomics

2016

Imamura, Hideo; Downing, Tim; den Broeck, Frederik Van; Sanders, Mandy J; Rijal, Suman; Sundar, Shyam; Mannaert, An; Vanaerschot, Manu; Berg, Maya; Muylder, Géraldine De; Dumetz, Franck; Cuypers, Bart; Maes, Ilse; Domagalska, Malgorzata; Decuypere, Saskia; Rai, Keshav; Uranw, Surendra; Bhattarai, Narayan Raj; Khanal, Basudha; Prajapati, Vijay Kumar; Sharma, Smriti; Stark, Olivia; Schönian, Gabriele; Koning, Harry P De; Settimo, Luca; Vanhollebeke, Benoit; Roy, Syamal; Ostyn, Bart; Boelaert, Marleen; Maes, Louis; Berriman, Matthew; Dujardin, Jean-Claude; Cotton, James A

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent Journal Article

In: eLife, 5 , pp. e12613, 2016, ISSN: 2050-084X.

Abstract | Links | BibTeX | Altmetric | Tags: drug-resistance, evolution, genomics

Mondelaers, Annelies; Sanchez-Cañete, Maria P; Hendrickx, Sarah; Eberhardt, Eline; Garcia-Hernandez, Raquel; Lachaud, Laurence; Cotton, James; Sanders, Mandy; Cuypers, Bart; Imamura, Hideo; Dujardin, Jean-Claude; Delputte, Peter; Cos, Paul; Caljon, Guy; Gamarro, Francisco; Castanys, Santiago; Maes, Louis

Genomic and Molecular Characterization of Miltefosine Resistance in Leishmania infantum Strains with Either Natural or Acquired Resistance through Experimental Selection of Intracellular Amastigotes Journal Article

In: PLOS ONE, 11 (4), pp. 1-15, 2016.

Abstract | Links | BibTeX | Altmetric | Tags: genomics, leishmania

Cuypers, Bart; Lecordier, Laurence; Meehan, Conor J; den Broeck, Frederik Van; Imamura, Hideo; Büscher, Philippe; Dujardin, Jean-Claude; Laukens, Kris; Schnaufer, Achim; Dewar, Caroline; Lewis, Michael; Balmer, Oliver; Azurago, Thomas; Kyei-Faried, Sardick; Ohene, Sally-Ann; Duah, Boateng; Homiah, Prince; Mensah, Ebenezer Kofi; Anleah, Francis; Franco, Jose Ramon; Pays, Etienne; Deborggraeve, Stijn

Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection Journal Article

In: mBio, 7 (2), 2016.

Abstract | Links | BibTeX | Altmetric | Tags: evolution, genomics