Publications

Show all

2021

Hees, Stijn Van; Cuypers, Bart; Bourgeois, Stefan; Groothuismink, Zwier M A; Meysman, Pieter; der Vlies, Pieter Van; de Knegt, Rob; Vonghia, Luisa; Michielsen, Peter; Francque, Sven; Laukens, Kris; Boonstra, Andre; Vanwolleghem, Thomas

Sorted B cell transcriptomes point towards actively regulated B cell responses during ongoing chronic hepatitis B infections Journal Article

In: Cellular Immunology, 362 , pp. 104283, 2021, ISSN: 0008-8749.

Abstract | Links | BibTeX | Altmetric | Tags: immunology, RNA-seq, transcriptomics, virology

Boullosa, Laurie Freire; Loenhout, Jinthe Van; Flieswasser, Tal; Waele, Jorrit De; Hermans, Christophe; Lambrechts, Hilde; Cuypers, Bart; Laukens, Kris; Bartholomeus, Esther; Siozopoulou, Vasiliki; Vos, Winnok H De; Peeters, Marc; Smits, Evelien L J; Deben, Christophe

Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer Journal Article

In: Redox Biology, pp. 101949, 2021, ISSN: 2213-2317.

Abstract | Links | BibTeX | Altmetric | Tags: cancer, genomics, RNA-seq, transcriptomics

Houtven, Joris Van; Cuypers, Bart; Meysman, Pieter; Hooyberghs, Jef; Laukens, Kris; Valkenborg, Dirk

Constrained Standardization of Count Data from Massive Parallel Sequencing Journal Article

In: Journal of Molecular Biology, pp. 166966, 2021, ISSN: 0022-2836.

Abstract | Links | BibTeX | Altmetric | Tags: multi-omics, normalization, proteomics, RNA-seq, transcriptomics

Logie, Emilie; Chirumamilla, Chandra S; Perez-Novo, Claudina; Shaw, Priyanka; Declerck, Ken; Palagani, Ajay; Rangarajan, Savithri; Cuypers, Bart; Neuter, Nicolas De; Turabe, Fazil Mobashar Hussain Urf; Verma, Navin Kumar; Bogaerts, Annemie; Laukens, Kris; Offner, Fritz; Vlierberghe, Pieter Van; Ostade, Xaveer Van; Berghe, Wim Vanden

Covalent Cysteine Targeting of Bruton’s Tyrosine Kinase (BTK) Family by Withaferin-A Reduces Survival of Glucocorticoid-Resistant Multiple Myeloma MM1 Cells Journal Article

In: Cancers, 13 (7), 2021, ISSN: 2072-6694.

Abstract | Links | BibTeX | Altmetric | Tags: cancer, transcriptomics

2020

Adriaensen, Wim; Cuypers, Bart; Cordero, Carlota F; Mengasha, Bewketu; Blesson, Séverine; Cnops, Lieselotte; Kaye, Paul M; Alves, Fabiana; Diro, Ermias; van Griensven, Johan

Host transcriptomic signature as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIV Journal Article

In: EBioMedicine, 55 , 2020, ISSN: 2352-3964.

Abstract | Links | BibTeX | Altmetric | Tags: immunology, leishmania, machine-learning, RNA-seq, transcriptomics

Deben, Christophe; Boullosa, Laurie Freire; Domen, Andreas; Wouters, An; Cuypers, Bart; Laukens, Kris; Lardon, Filip; Pauwels, Patrick

Characterization of acquired nutlin-3 resistant non-small cell lung cancer cells Journal Article

In: Cancer Drug Resistance, 3 , pp. [Online First], 2020, ISSN: 2578-532X.

Abstract | Links | BibTeX | Altmetric | Tags: cancer, drug-resistance, transcriptomics

2018

Krivoshiev, Boris V; Beemster, Gerrit T S; Sprangers, Katrien; Cuypers, Bart; Laukens, Kris; Blust, Ronny; Husson, Steven J

Transcriptome profiling of HepG2 cells exposed to the flame retardant 9,10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide (DOPO) Journal Article

In: Toxicology research, 7 (3), pp. 492-502, 2018, ISSN: 2045-452X, (c8tx00006a[PII]).

Abstract | Links | BibTeX | Altmetric | Tags: transcriptomics

Cuypers, Bart

A systems biology approach for a comprehensive understanding of molecular adaptation in** Leishmania donovani PhD Thesis

University of Antwerp, 2018.

BibTeX | Tags: genomics, LC-MS, leishmania, multi-omics, proteomics, RNA-seq, transcriptomics

Dumetz, F; Cuypers, B; Imamura, H; Zander, D; DtextquoterightHaenens, E; Maes, I; Domagalska, M A; Clos, J; Dujardin, J -C; Muylder, G De

Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent Journal Article

In: mSphere, 3 (2), 2018.

Abstract | Links | BibTeX | Altmetric | Tags: LC-MS, leishmania, metabolomics, multi-omics, RNA-seq, transcriptomics

Krivoshiev, Boris V; Beemster, Gerrit T S; Sprangers, Katrien; Cuypers, Bart; Laukens, Kris; Blust, Ronny; Husson, Steven J

Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq Journal Article

In: Toxicology in Vitro, 46 , pp. 178 - 188, 2018, ISSN: 0887-2333.

Abstract | Links | BibTeX | Altmetric | Tags: RNA-seq, transcriptomics

2017

Cuypers, Bart; Domagalska, Malgorzata A; Meysman, Pieter; de Muylder, Géraldine; Vanaerschot, Manu; Imamura, Hideo; Dumetz, Franck; Verdonckt, Thomas Wolf; Myler, Peter J; Ramasamy, Gowthaman; Laukens, Kris; Dujardin, Jean-Claude

Multiplexed Spliced-Leader Sequencing: A high-throughput, selective method for RNA-seq in Trypanosomatids Journal Article

In: Scientific Reports, 7 (1), pp. 3725, 2017, ISSN: 2045-2322.

Abstract | Links | BibTeX | Altmetric | Tags: leishmania, RNA-seq, transcriptomics

Dumetz, F; Imamura, H; Sanders, M; Seblova, V; Myskova, J; Pescher, P; Vanaerschot, M; Meehan, C J; Cuypers, B; Muylder, G De; Späth, G F; Bussotti, G; Vermeesch, J R; Berriman, M; Cotton, J A; Volf, P; Dujardin, J C; Domagalska, M A

Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression Journal Article

In: mBio, 8 (3), 2017.

Abstract | Links | BibTeX | Altmetric | Tags: genomics, leishmania, multi-omics, RNA-seq, transcriptomics